ABCB11 ELISA Kit for Human(Homo sapiens) | EIAab.comABCB11 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > ABCB11(Gene name) > Human

ABCB11 (Gene name),

Bile salt export pump (Protein name ), ABCBB_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ABCB11(BSEP);

Protein name:

Bile salt export pump;

Alternative:

ATP-binding cassette sub-family B member 11;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with HAX1.

Function:

Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

1321

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1300:

1321:

EELMAQKGAY | YKLVTTGSPI | S

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

O95342

STRING:

9606.ENSP00000263817

MIM:

601847

Pfam:

PF00664

UniGene:

Hs.658439

String:

O95342

KEGG:

hsa:8647

Uniprot:

O95342

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ELISA Kit for Human Bile salt export pump

Cat.:

E10415h

Price:

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Manual:

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Packing:

96T

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ELISA Kit for Human Bile salt export pump

Cat.:

E10415r

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MSDS:

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Packing:

96T

ELISA Kit for Human Bile salt export pump

Cat.:

E10415m

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96T

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ELISA Kit for Human Bile salt export pump

MSDS:

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CLIA Kit for Human Bile salt export pump

Cat.:

U10415h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Bile salt export pump

Cat.:

U10415r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Bile salt export pump

Cat.:

U10415m

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Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human Bile salt export pump

MSDS:

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Polyclonal Antibody for Human Bile salt export pump

Cat.:

P10415Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Bile salt export pump

Cat.:

P10415Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Bile salt export pump

Cat.:

P10415Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Bile salt export pump

Protein for Human Bile salt export pump

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis."
Strautnieks S.S. , Bull L.N. , Knisely A.S. , Kocoshis S.A. , Dahl N. , Arnell H. , Sokal E.M. , Dahan K. , Childs S. , Ling V. , Tanner M.S. , Kagalwalla A.F. , Nemeth A. , Pawlowska J. , Baker A. , Mieli-Vergani G. , Freimer N.B. , Gardiner R.M. , more...
Nat. Genet.20:233-238(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS PFIC2 GLY-297; GLU-461; GLY-482; ARG-982; CYS-1153 AND GLN-1268
2.

"Cellular localization and functional characterization of the human bile salt export pump (BSEP)."
Mol O. , Hooiveld G.J.E.J. , Jansen P.L.M. , Muller M.
Submitted (1999-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ALA-444
3.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"Two N-linked glycans are required to maintain the transport activity of the bile salt export pump (ABCB11) in MDCK II cells."
Mochizuki K. , Kagawa T. , Numari A. , Harris M.J. , Itoh J. , Watanabe N. , Mine T. , Arias I.M.
Am. J. Physiol.292:G818-G828(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-109; ASN-116; ASN-122 AND ASN-125
5.

"Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis."
Jansen P.L.M. , Strautnieks S.S. , Jacquemin E. , Hadchouel M. , Sokal E.M. , Hooiveld G.J.E.J. , Koning J.H. , De Jager-Krikken A. , Kuipers F. , Stellaard F. , Bijleveld C.M. , Gouw A. , Van Goor H. , Thompson R.J. , Muller M.
Gastroenterology117:1370-1379(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PFIC2 VAL-238 AND SER-336
6.

"Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population."
Saito S. , Iida A. , Sekine A. , Miura Y. , Ogawa C. , Kawauchi S. , Higuchi S. , Nakamura Y.
J. Hum. Genet.47:38-50(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ALA-444
7.

"FIC1 and BSEP defects in Taiwanese patients with chronic intrahepatic cholestasis with low gamma-glutamyltranspeptidase levels."
Chen H.-L. , Chang P.-S. , Hsu H.-C. , Ni Y.-H. , Hsu H.-Y. , Lee J.-H. , Jeng Y.-M. , Shau W.-Y. , Chang M.-H.
J. Pediatr.140:119-124(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PFIC2 LEU-284 AND ASP-1004
8.

"Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11."
van Mil S.W.C. , van der Woerd W.L. , van der Brugge G. , Sturm E. , Jansen P.L.M. , Bull L.N. , van den Berg I.E.T. , Berger R. , Houwen R.H.J. , Klomp L.W.J.
Gastroenterology127:379-384(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS BRIC2 GLY-186; GLY-297; THR-570; PRO-923; PRO-926; CYS-1050 AND HIS-1128
9.

"Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy."
Pauli-Magnus C. , Lang T. , Meier Y. , Zodan-Marin T. , Jung D. , Breymann C. , Zimmermann R. , Kenngott S. , Beuers U. , Reichel C. , Kerb R. , Penger A. , Meier P.J. , Kullak-Ublick G.A.
Pharmacogenetics14:91-102(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GLN-415; ALA-444; SER-591 AND VAL-677
10.

"Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis."
Noe J. , Kullak-Ublick G.A. , Jochum W. , Stieger B. , Kerb R. , Haberl M. , Muellhaupt B. , Meier P.J. , Pauli-Magnus C.
J. Hepatol.43:536-543(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS BRIC2 GLY-297 AND THR-432;CHARACTERIZATION OF VARIANTS BRIC2 GLY-297 AND THR-432
11.

"Genetic variability, haplotype structures, and ethnic diversity of hepatic transporters MDR3 (ABCB4) and bile salt export pump (ABCB11)."
Lang T. , Haberl M. , Jung D. , Drescher A. , Schlagenhaufer R. , Keil A. , Mornhinweg E. , Stieger B. , Kullak-Ublick G.A. , Kerb R.
Drug Metab. Dispos.34:1582-1599(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS VAL-206; ALA-284; LYS-299; ALA-444; GLY-616; ALA-619; VAL-677; HIS-698; VAL-865 AND GLN-958
12.

"Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver."
Meier Y. , Pauli-Magnus C. , Zanger U.M. , Klein K. , Schaeffeler E. , Nussler A.K. , Nussler N. , Eichelbaum M. , Meier P.J. , Stieger B.
Hepatology44:62-74(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ALA-444 AND VAL-677
13.

"Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury."
Lang C. , Meier Y. , Stieger B. , Beuers U. , Lang T. , Kerb R. , Kullak-Ublick G.A. , Meier P.J. , Pauli-Magnus C.
Pharmacogenet. Genomics17:47-60(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ALA-284; ALA-444; TYR-676; VAL-677; HIS-698 AND ARG-855;BIOPHYSICOCHEMICAL PROPERTIES;CHARACTERIZATION OF VARIANTS ALA-444; TYR-676; VAL-677 AND ARG-855

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